Tag Archives: immunotherapy

Study identifies TAK1 gene as key brake for cancer immunotherapy

Australian researchers have found that the TAK1 gene helps cancer cells survive immune system attacks, uncovering a mechanism that might limit the effectiveness of immunotherapy treatments. Cancer immunotherapies can work thoroughly, but in some cases they’re inadequate as a result of the survival processes built into tumors that help them resist immune system attacks. Researchers […]

Researchers develop recent approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers at Johns Hopkins Kimmel Cancer Center and Johns Hopkins University School of Medicine have developed a technique to evaluate which patients with metastatic triple-negative breast cancer might profit Immunotherapy. The work by computer scientists and clinicians was published October 28 in . Immunotherapy attempts to strengthen the body’s immune system to […]

Immunotherapy produces an entire response in stage IV lung cancer

On October 8, 2024, a brand new case report entitled “Complete and Durable Response to” was published in (Volume 11). Immunotherapy in stage IV non-small cell lung cancer involving the brain metastasis.” As highlighted within the summary of this report, about 20% of those are Lung cancer patients have brain metastases at diagnosis, which is […]

Groundbreaking humanized mouse model offers latest insights for the event of immunotherapy

A breakthrough in biomedical research guarantees latest insights into the event of immunotherapies and disease modeling. Scientists on the University of Texas Health Science Center in San Antonio have developed a humanized mouse model with a human immune system and human-like gut microbiome that’s able to eliciting specific antibody responses. The scientists were led by […]

Targeting epigenetic enzymes in dendritic cells to enhance cancer immunotherapy

Immunotherapy is one in every of the pillars within the fight against cancer and goals to enable the body’s own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from the so-called dendritic cells of the immune system influences their development and thus improves anti-tumor […]

Researchers discover potential metabolic goal for cancer immunotherapy

Researchers on the VIB-KU Leuven Center for Cancer Biology have identified a possible goal for cancer immunotherapy. The team, led by Professor Massimiliano Mazzone, found that the gene is some of the upregulated metabolic genes in immunotherapy-resistant tumors. Inhibiting this gene by pharmacological or genetic interventions led to raised T cell Infiltration, increasing the effectiveness […]

The intestinal bacterium Ruminococcus gnavus can enhance the consequences of cancer immunotherapy

About one in five cancer patients profit from immunotherapy – a treatment that uses the immune system to fight cancer. Such an approach to fighting cancer has achieved significant success in lung cancer and other diseases Melanoma, amongst others. Researchers are optimistic about its potential and are exploring strategies to enhance immunotherapy for cancers that […]

Expanding the treatment horizon for hypermutated urothelial carcinomas beyond immunotherapy

On April 25, 2024, a brand new editorial entitled “Therapeutic options for hypermutated urothelial carcinomas beyond immunotherapy” was published in (Volume 11). On this recent editorial, researchers from Sault Area Hospital and Northern Ontario School of Medicine discuss tumor mutation burden (TMB), a novel clinical biomarker for predicting response to checkpoint inhibitor immunotherapy in various […]